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My first Shiny app: fitting sigmoid curves – TLP
https://bernatv.wordpress.com/2016/12/01/my-first-shiny-app-fitting-sigmoid-curves
My first Shiny app: fitting sigmoid curves. Since the grad school I have been using R. For data analysis and (mainly) for preparation of nice plots. As with LaTeX. Fortunately, the community of software developers is very helpful and supportive. To the point where they write software that helps less skillful folks (like me) to create their own apps easier. Shiny. Is one of such frameworks. I chose it because it is fully R-based and natively integrated with RStudio. OK, enough introduction! How to use it?
Slava Bernat – TLP
https://bernatv.wordpress.com/author/vpbernat
I did my PhD in medicinal chemistry/chemical biology of G protein-coupled receptors and then explored some chemical biology of non-coding RNA as a postdoc. Currently I'm working in a small biotech company in San-Francisco Bay area as a research chemist. I'm writing about science, which catches my attention in rss feed reader and some random thoughts or tutorials. Mose et al. (Jørgensen lab) [ Nature Chemistry. Want something even cooler, here’s a dyotropic reaction! Hall, Roche, and West [ OL. Among chem...
Thesis in LaTeX. – TLP
https://bernatv.wordpress.com/2016/02/27/thesis-in-latex
When I was writing my diploma thesis in 2009, I wanted to do it somewhat ‘special’ and I tried to write it in LaTeX. More precisely in LyX. That time there were so many geeks around Internet that praised LaTeX to be superior to any other typesetting method that I was eventually persuaded to give it a try. That time I failed miserably. Eventually I ended up writing the diploma in OpenOffice. As you might guess, I took the hard way. What was the motivation? Positive side of LaTeX. Since output .pdf fil...
β2AR: old horse’s new tricks – TLP
https://bernatv.wordpress.com/2016/08/21/β2ar-old-horses-new-tricks
Β2AR: old horse’s new tricks. It’s almost four years since the Nobel prize in chemistry went to Brian Kobilka and Robert Lefkowitz for their contribution in our understanding of G protein-coupled receptor (GPCR) signaling. They did their most exciting work by studying β2 adrenergic receptor (β2AR). Yet, despite the titanic efforts, the receptor still holds lots of secrets from us. A little earlier biophysicists. From Brussels published a paper. A year ago researchers from Lefkowitz lab visualized. Recrui...
Remote cell reprogramming for diabetes treatment – TLP
https://bernatv.wordpress.com/2016/12/14/remote-cell-reprogramming-for-diabetes-treatment
Remote cell reprogramming for diabetes treatment. Since I’m not that long in diabetes business, two new Cell papers from Collombat. Labs looked quite sensational for me. Both are the products of multi-centered collaborations, and both report regeneration of insulin-producing beta-cells. Altering probes from Stuart Schreiber lab, resveratrol. And peptide hormone betatrophin. OK, the last one doesn’t count. Let’s start with the Kubicek lab paper, which found that common (yet Nobel-winning. Malaria drug, ar...
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Molecular Design: October 2012
http://fbdd-lit.blogspot.com/2012_10_01_archive.html
The focus of this blog is molecular design which can be defined as control of the behavior of compounds and materials by manipulation of molecular properties. Sometimes vampires get staked and soucouyants get salted. Adv Drug Deliv Rev. Hypothesis driven molecular design. In Silico Medicinal Chemistry. Facebook FBDD and Molecular Design Group. Drug Mergers Hurt in Every Direction (Save One). A most enjoyable headline. Thermodynamics for medicinal chemistry design. Those who cannot predict.discover? One o...
Molecular Design: January 2015
http://fbdd-lit.blogspot.com/2015_01_01_archive.html
The focus of this blog is molecular design which can be defined as control of the behavior of compounds and materials by manipulation of molecular properties. Sometimes vampires get staked and soucouyants get salted. Adv Drug Deliv Rev. Hypothesis driven molecular design. In Silico Medicinal Chemistry. Facebook FBDD and Molecular Design Group. Drug Mergers Hurt in Every Direction (Save One). A most enjoyable headline. Thermodynamics for medicinal chemistry design. Those who cannot predict.discover? It...
“For last year’… – TheMicroRead
https://themicroread.com/2013/01/01/for-last-year
Life organiser / motivation. 8220;For last year’…. 8220;For last year’s words belong to last year’s language and next year’s words await another voice” T.S. Eliot, the American Playwright. Click to share on Twitter (Opens in new window). Share on Facebook (Opens in new window). Click to print (Opens in new window). Click to email (Opens in new window). Click to share on LinkedIn (Opens in new window). Click to share on Google (Opens in new window). Click to share on Tumblr (Opens in new window). Create h...
Molecular Design: August 2012
http://fbdd-lit.blogspot.com/2012_08_01_archive.html
The focus of this blog is molecular design which can be defined as control of the behavior of compounds and materials by manipulation of molecular properties. Sometimes vampires get staked and soucouyants get salted. Adv Drug Deliv Rev. Hypothesis driven molecular design. In Silico Medicinal Chemistry. Facebook FBDD and Molecular Design Group. Drug Mergers Hurt in Every Direction (Save One). A most enjoyable headline. Thermodynamics for medicinal chemistry design. Those who cannot predict.discover? We of...
Molecular Design: May 2012
http://fbdd-lit.blogspot.com/2012_05_01_archive.html
The focus of this blog is molecular design which can be defined as control of the behavior of compounds and materials by manipulation of molecular properties. Sometimes vampires get staked and soucouyants get salted. Adv Drug Deliv Rev. Hypothesis driven molecular design. In Silico Medicinal Chemistry. Facebook FBDD and Molecular Design Group. Drug Mergers Hurt in Every Direction (Save One). A most enjoyable headline. Thermodynamics for medicinal chemistry design. Those who cannot predict.discover? And t...
Molecular Design: July 2012
http://fbdd-lit.blogspot.com/2012_07_01_archive.html
The focus of this blog is molecular design which can be defined as control of the behavior of compounds and materials by manipulation of molecular properties. Sometimes vampires get staked and soucouyants get salted. Adv Drug Deliv Rev. Hypothesis driven molecular design. In Silico Medicinal Chemistry. Facebook FBDD and Molecular Design Group. Drug Mergers Hurt in Every Direction (Save One). A most enjoyable headline. Thermodynamics for medicinal chemistry design. Those who cannot predict.discover? While...
Molecular Design: August 2014
http://fbdd-lit.blogspot.com/2014_08_01_archive.html
The focus of this blog is molecular design which can be defined as control of the behavior of compounds and materials by manipulation of molecular properties. Sometimes vampires get staked and soucouyants get salted. Adv Drug Deliv Rev. Hypothesis driven molecular design. In Silico Medicinal Chemistry. Facebook FBDD and Molecular Design Group. Drug Mergers Hurt in Every Direction (Save One). A most enjoyable headline. Thermodynamics for medicinal chemistry design. Those who cannot predict.discover? Howev...
Molecular Design: Molecular recognition, controlled experiments and discrete chemical space
http://fbdd-lit.blogspot.com/2015/07/molecular-recognition-controlled.html
The focus of this blog is molecular design which can be defined as control of the behavior of compounds and materials by manipulation of molecular properties. Sometimes vampires get staked and soucouyants get salted. Adv Drug Deliv Rev. Hypothesis driven molecular design. In Silico Medicinal Chemistry. Facebook FBDD and Molecular Design Group. Drug Mergers Hurt in Every Direction (Save One). A most enjoyable headline. Thermodynamics for medicinal chemistry design. Those who cannot predict.discover? Ash i...
Molecular Design: June 2014
http://fbdd-lit.blogspot.com/2014_06_01_archive.html
The focus of this blog is molecular design which can be defined as control of the behavior of compounds and materials by manipulation of molecular properties. Sometimes vampires get staked and soucouyants get salted. Adv Drug Deliv Rev. Hypothesis driven molecular design. In Silico Medicinal Chemistry. Facebook FBDD and Molecular Design Group. Drug Mergers Hurt in Every Direction (Save One). A most enjoyable headline. Thermodynamics for medicinal chemistry design. Those who cannot predict.discover?
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TLP – mostly science
Remote cell reprogramming for diabetes treatment. Since I’m not that long in diabetes business, two new Cell papers from Collombat. Labs looked quite sensational for me. Both are the products of multi-centered collaborations, and both report regeneration of insulin-producing beta-cells. Altering probes from Stuart Schreiber lab, resveratrol. And peptide hormone betatrophin. OK, the last one doesn’t count. Let’s start with the Kubicek lab paper, which found that common (yet Nobel-winning. Malaria drug, ar...
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Bernat Vidal Escultor
Inaugurada en Ormaiztegi una escultura de Bernat Vidal. El pasado día 14 de septiembre en la localidad gipuzkoana de Ormaiztegi, se inauguro una obra de Bernat Vidal. La escultura se ha instalado bajo el emblemático puente diseñado por el ingeniero frances Alexandre Gustave Eiffel. Publicado por Bernat Vidal. Enlaces a esta entrada. Enviar por correo electrónico. Publicado por Bernat Vidal. Enlaces a esta entrada. Enviar por correo electrónico. Suscribirse a: Entradas (Atom). NOTICIAS EN PRIMERA PERSONA.
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