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Welcome to the Edward Dennis Group

The Dennis Lab focuses on the biochemical, biophysical and cellular signaling roles of the phospholipases A2 enzyme family. We utilize purified recombinant enzymes to understand the basic mecanism of PLA2 function at lipid interfaces using a variety of techniques including mass-spectrometry. Additionally we examine the complex interactions of the PLA2 and cyclooxygenase enzymes and their down-stream signaling products in macrophage cell models.

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Welcome to the Edward Dennis Group | cobra.ucsd.edu Reviews

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The Dennis Lab focuses on the biochemical, biophysical and cellular signaling roles of the phospholipases A2 enzyme family. We utilize purified recombinant enzymes to understand the basic mecanism of PLA2 function at lipid interfaces using a variety of techniques including mass-spectrometry. Additionally we examine the complex interactions of the PLA2 and cyclooxygenase enzymes and their down-stream signaling products in macrophage cell models.

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1 lipid maps

2 phospholipase A2

3 phospholipases

4 Edward A. Dennis

5 Edward Dennis

6 macrophages

7 P388D1

8 inflammation

9 Lipid

10 Glue Grant

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Welcome to the Edward Dennis Group | cobra.ucsd.edu Reviews

https://cobra.ucsd.edu

The Dennis Lab focuses on the biochemical, biophysical and cellular signaling roles of the phospholipases A2 enzyme family. We utilize purified recombinant enzymes to understand the basic mecanism of PLA2 function at lipid interfaces using a variety of techniques including mass-spectrometry. Additionally we examine the complex interactions of the PLA2 and cyclooxygenase enzymes and their down-stream signaling products in macrophage cell models.

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Edward A. Dennis

http://cobra.ucsd.edu/group%20members/Edward_Dennis/edward_dennis.htm

Edward A. Dennis. Distinguished Professor of Chemistry, Biochemistry and Pharmacology. Department of Chemistry and Biochemistry. School of Medicine and Revelle College. University of California at San Diego. La Jolla, CA 92093-0601. Phone: (858) 534 - 3055. Fax: (858) 534 - 7390. Lipid Mediators in Health and Disease II -. Photos from the conference. European Federation for the Science and. Technology of Lipids 2007Award.

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Publications

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The Dennis group has over 360 publications on a large variety of topics and most recently related to lipidomics and metabolomics, eicosanoid metabolism, phospholipase structure and function, and lipid signaling. PDF - Complete Publication List.

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Group Members

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Click to see more pictures. Where all the work gets done.

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Welcome to the Edward Dennis Group

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