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CureFFI.org | cureffi.org Reviews
https://cureffi.org
Not if, when.
cureffi.org
The powerful protective effect of G127V
http://www.cureffi.org/2015/06/10/the-powerful-protective-effect-of-g127v
The powerful protective effect of G127V. Jun 10, 2015 ericminikel Cambridge, MA. Underwent massive positive selection during the kuru epidemic [ Mead 2009. From its origins 10 generations ago (the estimated time to most recent common ancestor of Fore G127V chromosomes) the variant rose to a 7% allele frequency in the most heavily affected regions, with not a single person carrying the variant falling ill with kuru. See also Glenn Telling’s commentary. Skeptics may note that the 127V transgenic mice in th...
Archives
http://www.cureffi.org/archives
Everything · no notes. 2016-08-19 — Presymptomatic imaging. 2016-08-16 — Native function update. 2016-08-02 — The role of microglia in prion disease. 2016-07-10 — CJD2016. 2016-07-06 — Mouse models of genetic prion disease. 2016-06-28 — Introductory prion reading list. 2016-06-03 — New Technologies Club lecture on cryo-electron microscopy. 2016-05-13 — Prion2016. 2016-05-08 — A mechanism of action hypothesis. 2016-04-27 — Differential scanning calorimetry. 2016-03-02 — What do we know about ApoE? 2015-11...
About
http://www.cureffi.org/about
My name is Eric Vallabh Minikel. And I’m on a lifelong quest to develop a treatment or cure for human prion diseases. I originally trained as a city planner at M.I.T. and was working as a software engineer and data analyst in the transportation sector when, in December 2011, I got some bad news. My wife and the love of my life, Sonia Vallabh, tested positive for a mutation (. Sonia and I set out on a quest. Where we work side by side in Stuart Schreiber’s lab. We now realize what once seemed an impos...
Two more chapters for 2-aminothiazoles
http://www.cureffi.org/2015/08/02/two-more-chapters-for-2-aminothiazoles
Two more chapters for 2-aminothiazoles. Aug 2, 2015 ericminikel Hamilton, MT. 2-aminothiazoles, typified by lead IND24 (above), are a series of antiprion compounds to which the Prusiner lab has devoted years of effort. They were first discovered in a phenotypic screen for compounds that reduce the accumulation of proteinase K-resistant PrP. In mouse neuroblastoma cells infected with RML prions (ScN2a cells) [ Ghaemmaghami 2010. And after extensive medicinal chemistry optimization [ Gallardo-Godoy 2011.
Summaries of the CJD2015 conference talks
http://www.cureffi.org/2015/07/12/summaries-of-the-cjd2015-conference-talks
Summaries of the CJD2015 conference talks. Jul 12, 2015 ericminikel Washington, DC. At the request of Debbie Yobs and Lori Nusbaum, these are my non-technical summaries of the talks at the CJD Foundation’s 2015 Family Conference held in Washington, D.C. on July 10-12, 2015, intended for a general audience. Which normally is a perfectly healthy thing. But if PrP. Folds differently and changes its shape, it can then induce other copies of PrP. If and only if. There are prions in the patient sample, those p...
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Plagnol lab's blog: Non-invasive pre-natal testing for chromosomal abnormalities: bioinformatics and the UK NHS process
http://plagnol-lab.blogspot.com/2014/07/non-invasive-pre-natal-testing-for.html
About me (and my work). Rare disease genetics- UCL exomes consortium. Wednesday, 9 July 2014. Non-invasive pre-natal testing for chromosomal abnormalities: bioinformatics and the UK NHS process. NIPT signal associated with a fetal micro. Deletion on chromosome 22 causing. Kitty Lo, a postdoctoral researcher in my group at UCL, just published a new. And an associated R package called RAPIDR (. What is non-invasive pre-natal testing (NIPT) and how does it work? NIPT in the UK: the RAPID project. As part of...
What do we miss with exome sequencing? | MacArthur Lab
https://macarthurlab.org/2014/07/21/what-do-we-miss-with-exome-sequencing
Extracting useful information from large genomic datasets. What do we miss with exome sequencing? The exome era turns five years old this fall, with the anniversary of the “Targeted capture and massively parallel sequencing of 12 human exomes” [ Ng 2009. Born at a time when whole genome sequencing cost. WGS has remained a last resort for a few reasons: it’s still a bit more expensive than WES, it produces more data we have to process and store, and despite some notable recent advances [ Ritchie 2014.
The MacArthur lab at ASHG2014 | MacArthur Lab
https://macarthurlab.org/2014/10/18/the-macarthur-lab-at-ashg2014
Extracting useful information from large genomic datasets. The MacArthur lab at ASHG2014. Several members of the MacArthur lab will be presenting at the American Society of Human Genetics Meeting in San Diego Oct 18-22, 2014. Here’s a rundown of what not to miss. And his wife Sonia Vallabh will speak in invited session #6: Crowdsourced Genetics. Room 6AB, Upper Level. Will present poster 1255S. Exhibit Hall, Poster 1255S. Will introduce the Human Knockout Project. Hall B1, Ground Level. A graduate studen...
inheritedpriondiseasesupport.org
Useful Links | Inherited Prion Disease Support Network
http://www.inheritedpriondiseasesupport.org/638210
Inherited Prion Disease Support Network. No results found for. About Inherited Prion Disease. News and Research Updates. Below are some links we hope you will find useful. We will continue to add to this page, please do let us know ( ipdsupportnetwork@hotmail.co.uk. If you have any recommendations you would like to add. The National Prion Clinic. The CJD Support Network. NHS Counselling and Genetic Counselling. NHS Choices Genetic Counselling Information. NPC support and Counselling Services. At the Nati...
Plagnol lab's blog: February 2013
http://plagnol-lab.blogspot.com/2013_02_01_archive.html
About me (and my work). Rare disease genetics- UCL exomes consortium. Monday, 11 February 2013. Genetics of cardiomyopathies: it's not easy. Congratulation to Luis Lopes (PhD at the UCL Heart Hospital) who just published his paper ( open access. In the Journal of Medical Genetics) on a high throughput sequencing screen of a cohort of hypertrophic cardiomyopathy. Genetics of inherited cardiac disorders are really complex. The attitude of cardiologists toward genetic diagnosis is changing. My point is that...
Debora S. Marks Lab
https://marks.hms.harvard.edu/people.html
Marks Lab Members and Collaborators. Debora S. Marks. Rohan defended his PhD on the evolution of laboratory and natural populations of Escherichia coli at Michigan State University in 2016. His main interest is molecular evolution. Rohan is especially interested in whether coevolution at the molecular scale is sufficient (or not) in driving the evolution of complex cellular lifeforms. Postdoc (joint with Chris Sander). Postdoc (joint with Chris Sander). Charlotta is a Bioinformatics PhD student from the ...
Plagnol lab's blog: We're hiring
http://plagnol-lab.blogspot.com/2013/05/were-hiring.html
About me (and my work). Rare disease genetics- UCL exomes consortium. Wednesday, 1 May 2013. A range of applicants are welcome, and the applicant's field can range from computer science to more abstract mathematics. Some experience with programming and scientific computation is expected however. The link for this application is here. Please get in touch with me if you are potentially interested in working with me at UCL and have any question about the application process. View my complete profile.
Plagnol lab's blog: Latest paper: Bayesian test for co-localisation between pairs of genetic association studies using summary statistics
http://plagnol-lab.blogspot.com/2013/05/latest-paper-bayesian-test-for-co.html
About me (and my work). Rare disease genetics- UCL exomes consortium. Monday, 20 May 2013. Latest paper: Bayesian test for co-localisation between pairs of genetic association studies using summary statistics. In this latest paper. Just submitted to arXiv, led by PhD student Claudia Giambartolomei) we want to answer the following question: given two genetic association studies both showing some association signal at a locus, how likely is it that the same variant is responsible for both associations?
Plagnol lab's blog: Three jobs @UCL
http://plagnol-lab.blogspot.com/2014/01/three-jobs-ucl.html
About me (and my work). Rare disease genetics- UCL exomes consortium. Sunday, 26 January 2014. Transcriptome analysis in blood and iPS cells of retinitis pigmentosa (RP) patients. Andrew Webster, Tony Moore, Michel Michealides, Shomi Bhattacharya (inherited retinal disorders), Pete Coffey (induced pluripotential stem cell technology) and myself. Sanjay Sisodiya, UCL Institute of Neurology and myself. Wellcome Trust, European Union, MRC. Four year PhD studentship:. Subscribe to: Post Comments (Atom).
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Santa Clarita Podiatrist - Valencia Foot and Ankle Center - Foot Doctor Santa Clarita, CA
Valencia Foot and Ankle Center. 27875 Smyth Ste 100. Valencia, CA 91355. Podiatrist - Santa Clarita. Valencia Foot And Ankle Center. Welcome to Valencia Foot And Ankle Center. We also know that convenience in the Santa Clarita area is important to your selection of a podiatrist. In these web pages youll find information about Valencia Foot And Ankle Center s office, including our Santa Clarita location, maps, directions, hours, insurance policies and appointment scheduling. Please feel free to co...We ho...
Cancer research fundraising events - CureFest
Purchase Tickets for Music Festival. Please Spread the Word. Help us spread the word about this amazingly exciting day. Share our sites through social media like facebook, www.facebook.com/curefest. Invite your friends and family. Soon you will be able to pre-purchase tickets for individuals, families or groups at www.CureFest.com. CureFest’s next event is our Annual CureFest Music Festival on Saturday, March 24th, 2018. Sponsorship opportunities are still available and your support is needed.
CureFest for Childhood Cancer
This Is A Custom Widget. This Sliding Bar can be switched on or off in theme options, and can take any widget you throw at it or even fill it with your custom HTML Code. Its perfect for grabbing the attention of your viewers. Choose between 1, 2, 3 or 4 columns, set the background color, widget divider color, activate transparency, a top border or fully disable it on desktop and mobile. This Is A Custom Widget. Schedule of Events – Tentative. A Night of Golden Lights. CureFest for Childhood Cancer. Over ...
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CureFFI.org
December 18, 2017. Protective PrP missense variants. December 15, 2017. Human prion propagation in cell culture. December 13, 2017. Targeting glutamate receptors in prion disease. December 11, 2017. Huntingtin becomes the huntingted. December 8, 2017. Skin, surgery, and CJD. November 10, 2017. Announcing the Prion Registry. October 25, 2017. July 25, 2017. July 19, 2017. Clinical research study launching at Massachusetts General Hospital. June 8, 2017. 567 more posts in archives→.
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Cure Fibroids Naturally
I cured my Fibroid - You can too! At last, A completely natural way to get rid of your fibroids. No Surgery, Drugs or expensive supplements. A method that can tackle the root cause of your fibroids once and for all, leaving you healthy, whole and fibroid free! A complete process - no surgery and no drugs. Discover and treat the underlying cause of your fibroids not just the symptoms. Key life experiences that can lead to fibroids. Techniques to restore balance, Relieve symptoms and activate Healing.
Natural Cure For Fibromyalgia
Natural Cure For Fibromyalgia. Wednesday, January 6, 2010. Because of the way that Blogger indexes the blog, I thought it would be easier to include links to my latest post in order. I hope this makes my Fibromialgia pages easier to navigate, Dustin. A brief introduction to my Fibromyalgia cure! Fibromyalgia Tender Point Chart. Links to this post. Monday, December 31, 2007. A brief introduction to my Fibromyalgia cure! Links to this post. Sunday, December 30, 2007. Links to this post. Links to this post.
Welcome to Cure Fibromyalgia |
Take a Chelation Therapy Break and Help your Fibromyalgia Feel. Transcutaneous Electrical Nerve Stimulator and fibromyalgia. Coping with Fibromyalgia and Jaw and Facial Tenderness. How Does Low Frequency Sound Therapy Help Fibromyalgia? Psychological Effects and Coping Strategies for FM Sufferers. Can Progesterone Therapy Grant Fibromyalgia Relief? Can Hyperbaric Oxygen Therapy Help Fibromyalgia Patients? What Does a Physiotherapist Do for Fibromyalgia Patients? A Toxic Attack On The Body, Mind And Spirit.
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