invitrozyme.com
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invitrozyme-website | invitrozyme.com Reviews
https://invitrozyme.com
Website for Invitrozyme Inc
invitrozyme.com
Products
http://www.invitrozyme.com/products.html
Concentration of the Preparation. Activity Using Probe Substrates. Development of Fluorescence or Luminescence-Based Assays. Enzyme Reaction Development in Various Tissues (blood, liver, kidney, lung, brain, heart, etc.) for Pharmacodynamic Assessment (Ex Vivo studies). Quantitation of Protein or mRNA Level. We conduct enzymatic assay development, and quantitation of biomarkers in various tissues for pharmacodynamic assessment. Cell and Tissue Fractionation:. Cytosol, S9 Fraction, Microsomes. Liver or ot...
Absorption
http://www.invitrozyme.com/absorption.html
Bi-Directional Transport with Caco-2 Monolayer for Investigation of Efflux and Influx Transport. Caco-2 Monolayer: 21-Day Model for Intestinal Permeability. Determination of permeability coefficient (. Across Caco-2 monolayer as a prediction of intestinal absorption. Bi-direction transport (A-to-B and B-to-A) for identification of efflux and influx transporter involvement of drug candidate absorption. Using the modified Franz-diffusion cells for the set-up.
Home
http://www.invitrozyme.com/index.html
Absorption - Drug-Drug Interactions - Metabolic Clearance - Metabolite Profiling - Protein Binding - Transporters - IVIVC. Invitrozyme is specialized in drug absorption and metabolism services and providing liver-related products (and other tissues) for drug discovery and development. We draw on exceptional talent of our scientists and collaborators with extensive experience from the pharmaceutical industry to conduct your metabolism studies.
Metabolism
http://www.invitrozyme.com/metabolism.html
Metabolic Stability and Clearance. Cytochrome P450-Mediated Drug-Drug Interactions. CYP450 Identification and Inhibition. Use of recombinant human P450 and HLM for identification of the P450 involved in the biotransformation of drug candidate. Inhibition assessment with probe substrates. Use of HLM and Probe substrates for assessment of P450 inhibition. Cryopreserved plateable hepatocytes for P450 induction assessment. Monitoring of CYP1A2 and CYP3A4 activity and mRNA level for induction potential.
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Cell Based Assays, Bioanalytical Laboratory Services, Platelet Function Assay | Invitrox
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invitrozyme-website
Absorption - Drug-Drug Interactions - Metabolic Clearance - Metabolite Profiling - Protein Binding - Transporters - IVIVC. Invitrozyme is specialized in drug absorption and metabolism services and providing liver-related products (and other tissues) for drug discovery and development. We draw on exceptional talent of our scientists and collaborators with extensive experience from the pharmaceutical industry to conduct your metabolism studies.
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