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例えば古典的老化研究者Comfort (1960) によると、 老化とは死にやすくなること であり、それは時間に支配された生物現象と定義されていた。 しかし別の老化研究者Arking (1998, 老化のバイオロジー) の最新の言葉を借りると、老化の定義において、 １ 時間軸があまり重要で無いこと、２ 個体老化と細胞老化の共通性があること. 染色体末端に特殊なリピート配列(テロメア配列)が発見され 、テロメア配列長は細胞分裂回数により減少し、テロメア維持のために特殊なRNA依存性DNAポリメレース (テロメラーゼ) が存在し Blackburnら 、テロメラーゼ強制発現によりヒト初代線維芽細胞老化抑制する事が報告され、ある決着を見た。 Http:/ www.kyoto-u.ac.jp/ja/news data/h/h1/news6/2013 1/140224 2.htm. Http:/ www.nikkan.co.jp/news/nkx1020140226eaaj.html. 我々の仕事がようやくJCB IF;11点 オンラインに載りました。
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